FOXN1 anticorps (N-Term)

N° du produit ABIN7603147

L’anticorps Lapin Polyclonal anti-FOXN1 a été validé pour WB et FACS. Il convient pour détecter FOXN1 dans des échantillons de Humain, Rat et Souris.

Aperçu rapide pour FOXN1 anticorps (N-Term) (ABIN7603147)

Antigène: FOXN1 (Forkhead Box N1 (FOXN1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXN1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-FOXN1 anticorps

Épitope: N-Term

Fonction: Anti-FOXN1 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-FOXN1 Antibody Picoband® (ABIN7603147). Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human FOXN1, which shares 85.7% amino acid (aa) sequence identity with mouse FOXN1.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Adriani, M., Martinez-Mir, A., Fusco, F., Busiello, R., Frank, J., Telese, S., Matrecano, E., Ursini, M. V., Christiano, A. M., Pignata, C. Ancestral founder mutation of the nude (FOXN1) gene in congenital severe combined immunodeficiency associated with alopecia in southern Italy population. Ann. Hum. Genet. 68: 265-268, 2004. 2. Amorosi, S., D'Armiento, M., Calcagno, G., Russo, I., Adriani, M., Christiano, A. M., Weiner, L., Brissette, J. L., Pignata, C. FOXN1 homozygous mutation associated with anencephaly and severe neural tube defect in human athymic Nude/SCID fetus. Clin. Genet. 73: 380-384, 2008. 3. Auricchio, L., Adriani, M., Frank, J., Busiello, R., Christiano, A., Pignata, C. Nail dystrophy associated with a heterozygous mutation of the nude/SCID human FOXN1 (WHN) gene. Arch. Derm. 141: 647-648, 2005.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur FOXN1

Antigène: FOXN1 (Forkhead Box N1 (FOXN1))

Autre désignation: FOXN1

Sujet:

Synonyms: Vitamin D-binding protein, DBP, VDB, Gc-globulin, Group-specific component, Gc

Background: The FOXN1 gene encodes a transcription factor that regulates the development of epithelial cells in the thymus and skin. FOXN1 is expressed in thymic epithelial cell precursors which interact with T-cell progenitors for T-cell development in the thymus, and thus plays an essential role in thymic development beginning in the embryo. FOXN1 is also expressed in keratinocytes, hair follicles, epithelial cells in the nail matrix bed, and cells of the choroid plexus.

Poids moléculaire: 69 kDa

ID gène: 8456

UniProt: O15353